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J Rheumatol

Hydration strategies: Aim for 6-8 glasses of fluid daily (about 1.5-2 litres), adjusting for activity level, climate and individual needs Sip fluids regularly throughout the day rather than consuming large volumes at once Monitor urine colour as a hydration indicatorpale straw colour suggests adequate hydration Consider oral rehydration solutions if experiencing diarrhoea or vomiting Moderate alcohol intake, which can worsen dehydration Note that caffeinated drinks count towards your fluid intake, though you may wish to moderate these if they worsen symptoms Note : If you have a condition requiring fluid restriction (such as heart failure or kidney disease), follow your healthcare provider's specific guidance on fluid intake

Before your visit, make sure your doctor knows about all the medications and supplements you take

3.3.2 Role of MOTS-c in OPG/RANKL-mediated osteoclasts In a UHMWPE model-induced osteolysis mouse model, MOTS-c was found to increase the intracellular osteoprotegerin (OPG)/RANKL ratio in osteocytes, thereby inhibiting osteoclastogenesis

Shotsy supports all major GLP-1 medications including Ozempic (semaglutide), Wegovy (semaglutide), Mounjaro (tirzepatide), and Zepbound (tirzepatide)