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GLP-1 medications are medications that mimic or activate incretin hormone pathways in the body
Recommended starting dose: 5 grams daily
Phase 2 MASLD substudy data demonstrated that retatrutide reduced mean relative liver fat by 82.4% at 24 weeks (12 mg dose)
The GIP receptor component enhances insulin secretion and may reduce nausea associated with GLP-1 activation
Losing muscle along with fat worsens metabolic rate and functional capacity
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