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An understanding of the appropriate format and dose for the desired effect 5

Unlike Palmitoyl Tripeptide-1 (Pal-GHK), which mimics GHKs ECM effects, GHK-Cus copper component amplifies its regenerative and antioxidant capabilities

However, in patients with IEMs, carnitine-TMAO conversion is not established, and it has been postulated that dietary protein restriction may mitigate gut microbial breakdown of supplemental l-carnitine, similar to what is seen in vegan/vegetarian individuals

The primary endpoints were relative change in weight and the proportion of participants losing 5 or 10% of baseline weight at week 56

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