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TLR-mediated neuroinflammation is particularly common in neurodegenerative disorders such as AD, with microglial TLR2 and TLR4 recognition of HMGB1 or Tau exacerbating age-associated disorders [213, 214]
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The tissue depth provides excellent cushioning for the needle, and the larger surface area makes site rotation easier
J Adv Vet Anim Res
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