In particular, microbial exposure has been shown to mitigate stress-induced behaviors and modulate immune responses, reinforcing the potential of microbial interventions in managing stress-related conditions (Bharwani et al., 2017)
Its efficacy is attributed to multi-target actions, including inhibiting ferroptosis via glutathione maintenance and reduced lipid peroxidation, as well as attenuating oxidative stress and neuroinflammation, and improving mitochondrial function, aligning well with PDs complex pathophysiology
According to a Clinicians Guide in a University of Virginia report published in 2018, the condition may not fully resolve for up to eight weeks, however (8) Neurologic symptoms, like tingling, numbness in hands and feet, or dizziness, generally improve in six to 12 weeks, and severe neurological symptoms, like difficulty walking, may not ever resolve completely
no health or sleep claims are attached to it
The most commonly reported adverse effects in clinical trials are gastrointestinal in nature, particularly during dose escalation