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12-Month Total Cost Comparison To illustrate the long-term cost implications, let us calculate the approximate total 12-month cost for a patient who follows the standard titration schedule: 0.25 mg for months 1-2, 0.5 mg for months 3-4, 1.0 mg for months 5-6, and a maintenance dose of 1.7 mg for months 7-12
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Oct 8 2020;383(15):1436-1446

The "L" refers to the molecule's chemical structure, while "reduced" refers to its active, antioxidant state

[8] [9] Some patients may experience a modest increase in heart rate (average 2-3 beats per minute), but this is not comparable to stimulant effects

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