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Although both treatments aim to support weight loss, they work differently

Zhao L, Peng Y, He S, Li R, Wang Z, Huang J, et al

On the next day, targeting plasmids (sgRNA or overexpression) were co-transfected with pMD2.G (#12259, Addgene) and psPAX2 (#12260, Addgene) plasmids at 1:1:1 molar ratio using Lipofectamine 2000 (#11668019, Thermo Fisher) at 1:2.5 ratio

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(PubMed) Chalasani NP, Sanyal AJ, Kowdley KV, et al