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While the body naturally makes collagen from amino acids in protein-rich foods like meat, bone broth, egg whites and spirulina, its natural quality and quantity decline with age, especially among postmenopausal women, the Cleveland Clinic says

This shift results in a lighter overall skin tone because pheomelanin yields a pinkish-yellow hue (as seen in people with fair skin or red hair), whereas eumelanin is responsible for brown or black pigmentation

Also, no effect of TRF on vascular endothelial function in middle-aged and older adults (Martens et al., ), despite other benefits (e.g., reduction of insulin resistance) (Hoddy et al., ) were reported

During the 300 ns to 500 ns MD simulation, hydrogen bonds between the protein and the ligand were analyzed (Table 2)

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