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DSIP administration did not significantly affect corticotropin-releasing-hormone (CRH)-stimulated or meal-induced ACTH and cortisol secretion, indicating thatcontrary to stress-protective effects reported in some animal studiesDSIP does not measurably blunt the human cortisol response

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One group was constantly illuminated and the other was exposed just to natural light conditions

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Its application has been studied extensively in clinical settings, especially for those dealing with obesity or insulin resistance