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Research Considerations Dosing Protocols: In phase 2 trials, doses ranged from 1 mg to 12 mg weekly, with escalation schedules (e.g., starting at 2 mg, increasing to 4 mg, 8 mg, or 12 mg over weeks)
Unique Batch IDs Every batch has its own ID, traceable from synthesis to shipment
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I.RaniaL.AragonaE.MannucciC.AlibrandiA.CalapaiG.et al (2018)
Adaptation Phase (Week 4-8): Many patients see clear improvement during this period as symptoms settle and daily routines adapt
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