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Angiogenesis (2007) 8

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The extra waiting time preserves peptide integrity that rushing destroys

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Hrelec M, et al

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Research protocols typically use 500mcg to 2mg per administration depending on study design, with localized dermal studies using higher doses (750mcg1mg) and anti-inflammatory models using lower doses (200mcg500mcg)

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Also, intranasal delivery generally produces fewer systemic side effects due to reduced peripheral exposure

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