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533 Additionally, in a rat model of obesity-related SAP, serum-derived Exos were found to stimulate the secretion of proinflammatory cytokines, including IL-1, IL-6, and TNF-, and exacerbate pancreatitis severity by promoting M1 polarization of adipose tissue macrophages

Diagnosis involves blood tests showing suppressed TSH with raised free T4 and/or T3, which supports hyperthyroidism

Whilst GLP-1 is not a digestive enzyme itself, it significantly influences digestive processes by slowing gastric emptying and affecting pancreatic function