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[6] These analyses are useful, but they are the weakest tier for a two-drug verdict: indirect comparisons inherit every difference between the underlying trials and cannot substitute for a randomised head-to-head

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This enhanced version of the linear perceptron uses multiple neuron layers, typically three or more, each applying nonlinear activation functions 61

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JCI Insight 5(16) Chan J, Scott R, Arjona Ferreira J, Sheng D, Gonzalez E, Davies M et al (2008) Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency