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The p38/MAPK pathway regulates microtubule polymerization through phosphorylation of MAP4 and Op18 in hypoxic cells

BPC-157 PubMed publications by year and study type, 1993 to June 2026 (n = 211) First, the post-2020 surge in the figure is driven by a proliferation of review articles that recycle the same data from the same rodent experiments

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Occurred in 8.8% of participants on 9 mg and 20.9% on 12 mg, compared to 0.7% on placebo Dose-dependent (higher dose, higher risk) Generally described as mild Rarely led to discontinuation Why this matters: Dysesthesia was not reported in the Phase 2 trial