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Previous studies have shown that H 2 S donors or related release systems, such as S-propargyl-cysteine (SPRC), can suppress the expression of M1-related inflammatory factors and promote the formation of M2-like phenotypes, suggesting that the Cys-GSH/H 2 S axis may jointly restrain pro-inflammatory programs by lowering the oxidative stress threshold and modulating signal transduction (79)

Do not exceed the recommended daily intake unless advised by a clinician

This technology allowed us to perform comprehensive investigation of properties of target metabolites in the blood as well as to assess their levels in different population cohorts

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Pneumococci were cultured in Todd-Hewitt broth supplemented with 0.5% yeast extract (THY), chemically defined medium (CDM) or tryptic soy agar (TSA) plates with sheep blood (3%) at 37C, 5% CO 2 as previously described (Lu et al., 2006)