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This article explores the sites of GLP-1 production, the mechanisms involved, and factors that influence its secretion, providing insight into both normal physiology and the rationale behind GLP-1 receptor agonist therapies used in type 2 diabetes and weight management

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For controlled skin studies, topical application removes the confounders introduced by injection no injection site reactions, no systemic distribution diluting local concentration, no injection technique variability across research subjects