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Long-term safety beyond 12 weeks has not been formally studied in large populations

A healthcare provider will determine the appropriate starting dose and titration schedule for each patient

This has led to the development of GLP-1 receptor agonists (such as semaglutide and liraglutide) and DPP-4 inhibitors, which are now established treatments for type 2 diabetes

GLP-1 receptor agonists may be considered when additional treatment goals include weight reduction, improved glycemic control, chronic kidney disease risk reduction, or lowering atherosclerotic cardiovascular risk, particularly in patients with obesity or established Atherosclerotic Cardiovascular Disease (ASCVD) [7, 16, 47]

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