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(NOTE: There is an ongoing debate about whether 5-Amino 1MQ should be classified as a small molecule or a peptide, but thats a discussion far beyond the scope of this article) It was discovered in 2017 by researchers at the University of Texas who were attempting to discover small, selective, and membrane-permeable inhibitors of an enzyme called nicotinamide N -methyltransferase (NNMT)

Kajimura, S., Aida, K

Instead, its a reaction to the infection itself being killed off

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Research has indicated potential benefits in treating arthritis, primarily through its regenerative properties and its ability to enhance angiogenesis