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Key advantage: Bypasses IGFBP binding more bioavailable in peripheral tissue
78 This study was followed by a phase 2, randomized, double-blind trial enrolling 178 cirrhosis patients with history of recurrent HE who received either GPB (6 mL twice daily for 16 weeks) vs
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Apart from the expression on cell membranes, cytoplasmic localization of ASGPR1 in hepatocyte-like cells was further shown, which has already been described for human liver tissue 31
Often, doctors recommend a drug like metformin as the first line of treatment or suggest weight loss through diet and exercise before introducing a GLP-1 receptor agonist
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