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Intervertebral discs were sampled, and ELISA and immunofluorescence analyses were performed
To determine the underlying mechanisms in detail, further study will be needed
Regular sterile water lacks this preservative and should only be used if the entire vial will be consumed within a few days
External stimuli responsive and non-cleavable internal stimuli responsive conjugations are beyond the scope of this review
Controlling NAD + -biosynthesis pathway Enhancing NAD + -biosynthesis is one alternative approach to elevate NAD + concentration through either increasing the activity of enzymes in NAD + -biosynthetic pathway or inhibiting the activity of enzymes in the side branch pathway
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