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A structural overlay of the ipratropium-bound structure and the occluded structure demonstrates that ipratropium in principle could fit within the occluded substrate-binding site cavity (Supplementary Fig
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Phase 2 (IGF-1Ea) : The splicing pattern shifts to favor IGF-1Ea, producing mature IGF-1 that drives differentiation and fusion of the expanded myoblast pool into mature myofibers
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