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Description

glabra L (Gancao), can inhibit the CCL2/CXCR4 axis to reduce M2 macrophage infiltration, while downregulating HMOX1/NOX4 to inhibit ferroptosis, and regulating the PPAR signaling pathway and fatty acid metabolism, thus forming immune-metabolic synergistic regulation (Shi et al., 2024)

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Reprod Biol 2005;5(1):5-17

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showed that ubiquitin-specific protease 7 (USP7) led to increased TFR1 and ferroptosis in a rat model of myocardial ischemia/reperfusion [77]

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