glp 1 and crohn's disease Frontiers Ever wondered how obesity, IBD,

The introduction of GLP-1 therapeutics has revolutionized the treatment of type 2 diabetes and obesity, with other potential indications under investigation

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This drug is a dual agonist that targets both GLP-1 and GIP receptors, which bolsters its ability to diminish body weight

Acknowledgements This work was supported by Ministero dellIstruzione, dellUniversit e della Ricerca of Italy, Progetto PONRicerca e Competitivit 20072013PON01_01802: Sviluppo di molecole capaci di modulare vie metaboliche intracellulari redoxsensibili per la prevenzione e la cura di patologie infettive, tumorali, neurodegenerative e loro delivery mediante piattaforme nano tecnologiche, and PON01_02512: Ricerca e sviluppo di bioregolatori attivi sui meccanismi epigenetici dei processi infiammatori nelle malattie croniche e degenerative

These benefits occur quickly following treatment initiation, suggesting that GLP-1 medicines may reduce cardiovascular events, at least in part, through weight loss-independent mechanisms