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Incretin mimetics (GLP-1 receptor agonists) directly mimic the action of the hormone GLP-1, whilst DPP-4 inhibitors (gliptins) prolong the activity of the body's own incretin hormones
2,3 The accumulation of these errors raises aneuploidy rates and is widely recognised as the single biggest contributor to lower implantation rates and higher miscarriage rates after 35
95% CI, 0.891.17), it was shown to be non-inferior to placebo in terms of cardiovascular safety ( The first study to demonstrate superiority over placebo was the LEADER study, in which 9,340 patients were assigned to either liraglutide or placebo
Conings S, Tseke F, Van den Broeck A, et al
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