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In the course of minutes, ACTH stimulates the adrenal glands to release glucocorticoids (GCs)
On the contrary, SB has no effect on cyclin E and cdk2, which are gene products associated with G1 phase of the cell cycle (Lee et al., 2004d)
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however, it leads to dependence when combined with opioids such as hydrocodone and oxycodone
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