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For patients experiencing heartburn while on GLP-1 therapy, several evidence-based management strategies can provide relief without necessitating medication discontinuation

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However, the circulating semaglutide concentration following administration is more variable following oral administration than subcutaneous injection, which might reflect poorer absorption [29]

Citation124 Recently, first-in-human clinical trials showed that fecal microbiota transplantation (FMT) improved the efficacies of anti-PD-1 immunotherapy in patients with anti-PD-1-refractory metastatic melanoma, while also reprogramming the gut microbiome