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Exact dosing varies by experimental design and species but generally follows preclinical trial standards for NNMT inhibitors
Sterile water for injection has no preservative and must be used immediately after opening
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The preferred format will depend on the objectives of each laboratory and the design of individual research protocols
Most rodent studies used: 10 micrograms/kg 100 micrograms/kg Administration routes varied by study: Intraperitoneal injection Subcutaneous injection Oral administration in drinking water Example reference: Sikiric et al., 2018 These dosages reflect controlled laboratory conditions and are not generalised outside experimental models
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