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Research has focused on its role in fat metabolism, adipogenesis inhibition, and metabolic regulation
However, for the same concentration range, a constant exposure can yield a harmful depletion of GSH to 30% of normal after 14 hours, indicated by the black-dashed line (Fig
The mechanisms operate through entirely different receptor systems and signaling pathways
Safety in these populations cannot be assumed based on the existing trial data
As a result, aside from its protective role in -cells, butyrate has been proposed as a direct regulator of insulin secretion via GPR-mediated signaling
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