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When cost is not an issue, the ADA recommends choosing a second-line medication from one of the following: dipeptidyl peptidase-4 inhibitors (DPP4i), glucagon-like peptide-1 receptor agonists (GLP-1-RA), or sodium/glucose co-transporter inhibitors (SGLT2i) [3]

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HUA-associated left ventricular wall thickening can be ameliorated by the FA oxidation-promoting agent LC

A dramatic cut in calories can further reduce essential nutrient intake, making deficiencies more likely