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The most common side effects among the trial group were nausea, diarrhea and vomiting
However, the authors suggested that carnitine deficiency cannot be the only reason for fatal VHT, because a 3.5-year-old girl developed hepatic failure under VPA therapy despite normal serum carnitine values, and died despite oral L-carnitine supplementation
Older adults People over 65 generally tolerate GLP-1 medications well, but the transition period carries higher risk for dehydration, hypotension, and falls related to GI side effects
This increased risk was observed in patients taking semaglutide for diabetes and weight management
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