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Methods We performed a retrospective chart review evaluating and characterizing glucagon-like peptide-1 receptor agonist exposures reported to a single poison center between 2006 and 2023

Theres limited data on whether microdosing leads to meaningful, sustained weight loss

Slowing the ramp to the label cadence (2.5 mg start, 2.5 mg steps, four-week holds) dropped that to mid-single digits at every maintenance dose, at no cost to the 12-week result, and the dedicated slow-titration trial reached placebo range. Reaching 15 mg is not the problem

They slow the movement of food through the stomach, so people stay satisfied for longer after a meal

Animal testing is the first stage, and human testing is the second stage