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In a widely cited New England Journal of Medicine trial, adults with overweight or obesity who used once-weekly semaglutide alongside lifestyle intervention lost substantially more weight than the placebo group

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ONE Innovation Labs' research-first approach will provide formulators with the clinical backing necessary for substantiated marketing claims

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Body composition testing reveals that many of these patients are losing significant skeletal muscle mass, effectively depleting their metabolic engines despite reaching a "normal" BMI

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