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For some individuals, bariatric or metabolic surgery may also be an option, depending on their overall health, related conditions, and previous treatment history

Tirzepatide at the highest doses (15 mg) may be associated with slightly more GI side effects, which makes sense given its additional GIP receptor activity

The body composition effects of sustained, physiologically-dosed GH secretion reduced visceral fat, increased lean mass generally improve insulin sensitivity over time

Ozempic and Rybelsus cost around $1000/month