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However, despite these efforts, some studies still exhibited unexplained heterogeneity, introducing a potential source of bias into our findings

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GoodRx describes these prescription-only medications as having "good clinical data showing that they're safe and effective when used as directed" under a provider's supervision (goodrx.com)

So much of the experimentation with GLP-1s is happening outside traditional research models, careful clinical trials and even the health system

Special Concerns: Historically, oral malignant melanoma was reported to progress more rapidly in pregnant females for unknown reasons