resistance to semaglutide and Insulin | How GLP-1s Work Compounded Semaglutide for Insulin Resistance

The study, which tested the drug in 529 patients with obesity and heart failure with preserved ejection fraction (HFpEF), demonstrated a 16.6-point increase at 52 weeks, with regard to the Clinical Summary Score (CSS) on the Kansas City Cardiomyopathy Questionnaire (KCCQ) a measure of symptoms of heart failure in comparison to an 8.7-point increase in the placebo group

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The structural similarity to semaglutide is notable

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But if something has a particularly prominent benefit, and theres a fairly easy strategy for side effects, for instance, tremor that can be treated with beta blockers or GI upset that could be treated with proton pump inhibitors