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Regenerative Medicine , 16(3), 245-257

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The evidence was based on experimental data only briefly described in the patent and included models of: gastric ulcers, heart damage, liver damage, pancreatic injury, kidney damage, experimental diabetes, fever, edema, rhinitis, bone fracture, burns, skin wounds, hypersensitivity reactions, pupil dilation, colon injury, tumour growth, radiation injury, red blood cell development, fertility and lactation, tooth damage, several types of central and peripheral nerve damage, and survival from infection with Trichinosis (i.e., tapeworms) as well as several viruses

doi: 10.1016/j.chom.2011.04.006 6 NaikSLarsenSBGomezNCAlaverdyanKSendoelAYuanSet al

To demonstrate specificity of the effect, we sought to rescue the decreased mEPSC frequency by pretreating with pyroglutamate (PGA), the precursor of glutamate that is synthesized downstream of GGT, which is blocked by acivicin (Fig