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Research Highlights Metabolic Regulation and Anti-Obesity Effects: Potent inhibition of nicotinamide N-methyltransferase (NNMT) increases cellular NAD and S-adenosylmethionine (SAM) levels, enhances polyamine flux, boosts energy expenditure, and suppresses lipogenesis
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However, it is important to understand that 24 weeks, while substantial for clinical trials, provides limited information about safety with years-long continuous use
[13] [21] Pfizer Inc
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