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Evidence standard: Every major claim is graded in the evidence ledger below

Examples include: ( Glycyrrhiza glabra , Licorice) and derivatives (Glycyrrhizic Acid, Glycyrrhetinic Acid, Licochalcone): Known for their anti-inflammatory properties but may increase cortisol levels and worsen eczema symptoms in some cases

Female participants gained less lean body mass than males

Neuroendocrine Effects Graf and Kastin (1984) reviewed the multiple physiological effects of DSIP beyond sleep, including its interactions with the HPA axis, pain modulation, and thermoregulation

Patch testing remains essential before widespread application