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High-dose IV vitamin C for cancer remains investigational and is not an approved or proven treatment

However, the assays fail to detect deficiency in older patients, even when it is severe enough to precipitate neuropsychiatric disease

The use of NNMT inhibitors as a potential obesity treatment has been investigated preclinically 8,9,13 , and observational clinical data suggests that increased NNMT expression and activity correlate with increased incidence of Type 2 diabetes (T2D) and risk of obesity, respectively 10,11

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