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Management of lower back pain in patients taking semaglutide should follow evidence-based guidelines for acute and chronic lower back pain, with consideration of the patient's overall metabolic health and treatment goals

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Meanwhile, a 2020 meta-analysis found no significant effect of berberine on body weight or BMI, but did find an effect on the waist-to-hip ratio

Recent findings on extra-pancreatic GLP-1 receptors on liver sinusoidal endothelial cells and hepatic stellate cells help clarify these diverse effects and may explain the survival benefits noted in patients with cirrhosis