Two of the most frequent causes are kidney stones or high calcium excretion (hypercalciuria) or high phosphorus in the urine (phosphaturia)
Retatrutide, still in Phase 3, reaches 24.2% You qualify if your BMI is 30 or higher, or 27 or higher with one obesity-related condition like type 2 diabetes, high blood pressure, high cholesterol, or sleep apnea Starting July 1, 2026, Medicare covers Wegovy, Zepbound KwikPen, and Foundayo through the GLP-1 Bridge at roughly $50/month for eligible beneficiaries NovoCare lists Wegovy self-pay routes from $149/month for tablets and $199/month introductory pen fills, then $349-$399 depending on dose
The principal distinction lies in tolerability rather than efficacy
Zhang S, Xu P, Zhu Z, Zhou L, Li J, Zhou R, et al
In Phase 2 clinical trials, the average duration of diarrhea episodes for Retatrutide users was just 1-3 weeks