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In obesity, abnormal adipose metabolism transports large amounts of free fatty acids to the liver, increasing hepatic fat synthesis, decreasing fat breakdown, and ultimately causing hepatic steatosis
Thyroid conditions alter the excretion of magnesium in the kidneys Altered thyroid states (such as those that occur with Hashimotos) can make your body eliminate more magnesium than you want it to in your kidneys
This all goes hand-in-hand with anti-aging benefits and overall general improved levels of wellbeing
Some studies suggest the quinolinium structure is sufficiently NNMT-selective that it should not broadly deplete SAM, but the wider metabolic picture remains an active research consideration
Inflammatory regulation
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