Originally developed as a treatment for diabetes, uptake has been staggering since the drugs were approved for weight loss, reflecting GLP-1s efficacy and growing acceptance
Clinical guidelines support the use of these medications for patients with obesity or type 2 diabetes when lifestyle modifications alone are insufficient
The BALANCE Model, announced December 2025, creates a Medicare GLP-1 payment demonstration beginning July 2026
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In contrast, compounded medications are often tailored for individual patients, which can make it challenging to establish a standardized efficacy profile