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I explained this is not a character flaw it is chemistry and hormones: Aromatase in adipose converts testosterone to estrogen reduced testosterone, increased estrogen fatigue, mood changes, lower muscle mass, more abdominal fat, impaired sperm and erectile function Cortisol and insulin under chronic stress and poor sleep elevate appetite (comfort foods), drive fat storage (especially visceral), and magnify insulin resistance (Bornstein et al., 2018) Ghrelin-Leptin-GLP-1 axis : Ghrelin increases hunger Leptin resistance blunts satiety signals Impaired GLP-1 signaling reduces fullness Chronic inflammation from adipokines fuels metabolic dysfunction His struggle is biochemical, not moral
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In further support of this notion, GLP-1R agonists can still reduce food intake when the aversive pathways of the AP are inhibited
When used in combination with diet & exercise, MIC/B12 amplifies the bodys ability to break through weight loss stagnation and build lean muscle mass
A recent study found both NAD and B12 to be effective in increasing telomere length, thereby slowing the aging process
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