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For patients in active weight loss or GLP-1 programs, adequate B12 supports red blood cell formation, oxygen delivery, and energy production, which makes it easier to maintain movement, preserve lean mass, and engage with the plan instead of slipping into exhaustion

This situation increases the risk of instability

For weight loss patients who struggle to maintain exercise routines because of low energy, B12 injections address the nutritional foundation that makes sustained physical activity possible

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Reviews of the literature continue to emphasise that the evidence base is largely preclinical