A 2025 systematic review, Vasireddi et al., HSS J 2025, screened hundreds of articles and found the BPC-157 orthopaedic base to be almost exclusively animal or low-level studies, with only isolated small human reports and no rigorous randomised trials
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These contradictions may indicate the spaciotemporal specificities for LOXs response and regulations, which suggest that the response of LOXs may vary at various stages of organ development