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Excess of glutamate at the synaptic cleft results in excessive firing of neurons, thereby increasing the influx of calcium which can be toxic to neurons 32
Bergmann et al
Ann Otol Rhinol Laryngol 1987
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placebo), most of them (liraglutide, semaglutide SC, dulaglutide, albiglutide, and efpeglenatide) have also demonstrated a reduction in MACE with respect to placebo, while weekly exenatide or oral semaglutide showed a tendency to reduce MACE
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