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doi: 10.7717/peerj.20346 218 ThiamHRWongSLWagnerDDWatermanCM

Iron: The body needs adequate iron levels to maintain proper levels of hemoglobin, which helps carry oxygen through the body

The synergistic action of these three components inhibits iron-dependent lipid peroxidation, blocks iron-induced cell death in renal tubular cells, significantly reduces oxidative damage and inflammatory responses, and ultimately restores renal function [92]

Since SIRT-1 has also been known to play a critical role in regulating mitochondrial function and biogenesis, we checked the mitochondrial cytochrome c levels in the liver and kidney of control Wistar and GK rat liver and kidney

In preclinical studies of cancer cell lines and tumor xenografts, auranofin exhibits remarkable sensitivity across various forms of drug-resistant cancer cells, including ovarian cancer with a cisplatin-resistant phenotype [235]