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If your typical dose is 25 units or less, consider using a 0.3 mL syringe for better precision
Trials suggest its side effect profile looks a lot like whats been seen with other GLP-1 drugs like Wegovy and Zepbound
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Continue daily during loading (7 to 21 days depending on skin type), then switch to 0.5 mg once or twice weekly for maintenance
Two estimands (treatment regimen estimand and efficacy estimand), based on the ICH E9(R1) guidance 32 , were used to assess treatment efficacy from different perspectives and accounted for intercurrent events differently
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