The interest and use of nutraceuticals that can play a supportive role in health and skin aging has increased dramatically in the last 10 years, with products containing vitamin C and E, collagen, omega-3 fatty acids, and antioxidants such as curcumin, glutathione, and resveratrol, which have multiple anti-inflammatory, protective effects against oxidative stress and age-related decline in cellular function [79,80,81]
Hyperpigmentation: 4% niacinamide reduces melasma severity, and 5% formulations show tone improvement when paired with antioxidants and tranexamic acid
Moreover, we excluded patients and controls who suffered from neurodegenerative and neuroinflammatory disorders, such as chronic fatigue syndrome [54], Parkinsons or Alzheimers disease, multiple sclerosis, stroke, or systemic (auto)immune diseases such as diabetes mellitus, psoriasis, rheumatoid arthritis, inflammatory bowel disease and scleroderma, and liver and renal disease
Vitamin C (500mg) provides powerful antioxidant protection and immune support , paired with Vitamin E for cellular defense against oxidative stress
Bioavailability means your body can actually absorb and use the nutrients instead of just passing them through